Side effects of Levaquin may include: Abdominal pain, anxiety, bad taste, constipation, diarrhea, dizziness, fatigue, fungal infections, gas, general feeling of illness, headache, hives, indigestion, itching, lack of appetite, nausea, nervousness, rash, sleeplessness and sleep disorders, sweating, swelling, tremors, vaginal discharge, vaginal inflammation, vomiting, and yeast infection. If any of these symptoms occur, contact your physician. In rare cases, Levaquin has caused convulsions and other nervous disorders. If you develop any warning signs of a nervous reaction - ranging from restlessness and tremors to depression and hallucinations - stop taking this medication and call your doctor. Levaquin may cause dizziness or light-headedness. Do not drive or operate machinery until you know how this drug affects you. Hypersensitivity to quinolone antibiotics can, in rare instances, lead to severe illnesses ranging from blood disorders to liver or kidney failure. The first sign of a developing problem is often a rash; so you should stop taking Levaquin and check with your doctor when any type of skin disorder appears. A case of diarrhea during Levaquin therapy could signal development of the potentially dangerous condition known as pseudomembranous colitis, an inflammation of the bowel. Call your doctor for treatment at the first sign of a problem. Stop taking Levaquin, avoid exercise, and call your doctor if you develop pain, inflammation, or a rupture in a tendon. Quinolone antibiotics have been known to cause tendon rupture during and after therapy. If you have a kidney condition, make sure the doctor is aware of it. Your dosage may need to be lowered.

Levaquin has been known to cause dangerous allergic reactions as soon as you take the first dose. Stop taking Levofloxacin and call your doctor immediately if you develop any of the following warning signs: Skin rash, hives, or any other skin reaction; Rapid heartbeat; Difficulty swallowing or breathing; Swelling of the face, lips, tongue, or throat.